How does array cgh work

This technology offers greater sensitivity, higher resolution, and can detect large regions of homozygosity, such as may be observed in uniparental disomy. This is therefore expected to be of benefit to the diagnostic pathway.

This change will not affect sample requirements or referral pathways and will not be expected to have a detrimental impact on turnaround times. The wet laboratory work will be undertaken by the Newcastle Genetics Laboratory with the analysis, reporting and issuing of results all being performed by the Leeds Genetics Laboratory. Users will during this transition receive both oligo and SNP reports, depending on the technology used, until the backlog of samples processed by oligo array has been reported.

The reports will stay in the current format with minor changes. Professional judgement is used to determine which patients are tested, in line with current lab policy. Please note: All patients who are eligible for array CGH need to have had this test completed before a referral to Clinical Genetics can be accepted. The laboratory will require a minimum of 1ml peripheral blood in an EDTA tube purple top with a Cytogenetics and DNA joint referral card which you can download from here.

Please complete with comprehensive clinical details. The laboratory turnaround times are taken from the ACGS Association for Clinical Genetic Science professional best practice guidelines and are as follows:. FISH probes. Samples from neonates are prioritised as urgent and the laboratory endeavours to obtain a result within 14 days. The method uses a Next Generation Sequencing approach to look for copy number variation in the genome in a similar way to array CGH.

Thank you very much. I love this course because I love biology and genetics from my childhood itself. Overall, l love this course very much. Its a good start for me who have no knowledge about genomic medicine and this will be my foundation to further study in Msc genomic medicine. This was an excellent course. It was very clear and easy to follow even though some of the content was technical. The content was bite sized so you could snack on it when you felt like it and this helped me to complete the course.

There was a module on ethics and responsibility which was important given that so many people are being genetically tested nowadays. It clearly explained the complexities of genetic testing and the forum responses highlighted how differently people think about this area.

There were many quizzes for free with feedback. I enjoyed this course. Category: FutureLearn Local. Category: FutureLearn Local , Learning. We offer a diverse selection of courses from leading universities and cultural institutions from around the world. These are delivered one step at a time, and are accessible on mobile, tablet and desktop, so you can fit learning around your life. You can unlock new opportunities with unlimited access to hundreds of online short courses for a year by subscribing to our Unlimited package.

Build your knowledge with top universities and organisations. Learn more about how FutureLearn is transforming access to education. Learn more about this course. Many things became clear to 22 Aug, Many things became clear to me now about genetics. Visit the course. Excellent course special on the 06 Jun, Great Course 06 Jun, It was a valuable course 18 May, My interesting Course 03 Jul, Overall, l The Genomics Era: may not be nee Very good and informative 20 Aug, Engaging course, clearly explain