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Top of Page. Most people who are infected develop mild symptoms or no symptoms at all. In people who develop severe disease, initial symptoms include fever, chills, headache, fatigue, nausea and vomiting. The disease can progress to inflammation of the brain encephalitis and is often accompanied by seizures. Coma and paralysis occur in some cases. Diagnosis is based on a combination of clinical signs and symptoms and specialized laboratory tests of blood or spinal fluid.

These tests typically detect antibodies that the immune system makes against the viral infection. There is no specific treatment. Severe illnesses are treated by supportive therapy which may include hospitalization, respiratory support, and intravenous fluids.

JE vaccine is recommended for persons moving to a JE-endemic country to live, longer-term e. JE vaccine also should be considered for shorter-term e.

Vaccination also should be considered for travelers to endemic areas who are uncertain of specific duration of travel, destinations, or activities. JE vaccine is not recommended for travelers with very low risk itineraries, such as shorter-term travel limited to urban areas or travel that occurs outside of a well-defined JE virus transmission season.

The duration of protection is unknown. A booster dose may be given if the primary two-dose vaccination series was given one year or more previously and there is continued risk of exposure. Pain and tenderness are the most commonly reported symptoms. If you develop any worrying symptoms after being vaccinated, contact your GP as soon as possible or call NHS for advice.

Most people can have the Japanese encephalitis vaccination safely, but you should tell the doctor or nurse before being vaccinated if you have a high temperature fever , or if you're pregnant or breastfeeding. It may also not be recommended if you're pregnant or breastfeeding as there's a theoretical risk of problems resulting from the vaccine being passed to your baby. The Japanese encephalitis vaccine is not usually recommended for children less than 2 months old because it's unclear how safe and effective it is for this age group.

You should not have the vaccine if you have had a severe allergic reaction anaphylaxis to it or any of its ingredients in the past. Various types of insect repellent are available. Page last reviewed: 01 February Next review due: 01 February Japanese encephalitis vaccination The vaccine gives protection for more than 9 out of every 10 people who have it.

You should get vaccinated if you're: planning a long stay in a high-risk country usually at least a month visiting a high-risk area during the rainy season or where there's a year-round risk because there's a tropical climate visiting rural areas in a high-risk country, such as rice fields, marshlands or somewhere close to pig farms taking part in activities while in a high-risk country that may increase your risk of becoming infected, such as cycling or camping working in a laboratory with potential exposure to the virus The vaccine is not available on the NHS, so you'll need to pay for it.

Other should be offered a first booster dose at months following the primary course, prior to re-exposure to JE virus. Others should be offered the first booster dose at months following the primary course prior to re-exposure to JE virus. In situations where the primary course days 0,28 or days 0,7 plus the first booster has been interrupted, the schedule should be resumed, and not restarted. Adults aged years can be vaccinated using a licensed accelerated schedule as follows: first dose at day 0, second dose: 7 days after first dose.

With both schedules, the primary immunisation schedule first and second dose should be completed at least one week prior to potential exposure to JE. Use of this accelerated schedule can also be considered off license for travellers 2 months years of age and those over 65 years of age when time is short. Therefore, travellers may not be able to complete their vaccination course overseas with this vaccine. Home Diseases in Brief Japanese encephalitis. Japanese encephalitis.

Prevention The risk of acquiring JE can be reduced by insect bite avoidance, particularly between the hours of dusk and dawn, when Culex mosquitoes are most active. Duration of protection, beyond two years after the first booster is uncertain.

Children aged 3 to 17 years 0.



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