How does granulation work

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Freezers Spiral Freezers. Homogenizers Homogenizer Compression Block. Valves and components for industrial refrigeration Components for industrial refrigeration Valves for industrial refrigeration. The dry granulation process readily accommodates both batch and continuous operations. This flexibility makes it ideal for small-scale and large-scale material processing applications. In material processing facilities, the key to maximizing profits is adopting more cost-effective processing techniques and technologies.

Dry granulation serves as a lower-cost method of processing powder and powder blends. It does not require the use of a liquid binding agent, which eliminates the need for separate moisture addition and material drying stages. Compared to wet granulation, this distinction saves on material, labor, and energy costs.

The basic structure of all Alexanderwerk roller compactors, in particular of our WP Pharma Series can be described as follows:. Dry granulation plays a critical role in the manufacture of numerous products for various industries.

If you want to learn more about the process or require material processing equipment for your facility, turn to the experts at Alexanderwerk. At Alexanderwerk, we specialize in dry granulation technology. We have the expertise and experience to design and build a roller compactor or entire dry granulation process train to meet your needs..

We maintain a multi-million dollar parts inventory to keep your equipment running and in good condition. To find out more about the dry granulation process or our roller compaction products, contact us today. Download Brochure. Dry Granulation. What Is Dry Granulation? In principle, two different processes for the production of granules can be used.

Wet granulation Dry granulation In so-called wet granulation, binders are added in liquid form to the powders. The addition of binders with subsequent drying process is not required here Roller compaction is a well-established manufacturing process accepted in multiple industries around the world It produces densified material by compressing powders between two counter-rotating rollers. Advantages of Dry Granulation Compared to other material processing methods, dry granulation offers a number of advantages, such as: Smaller Space Requirements In material processing facilities, floor space is always at a premium.

Broader Processing Versatility The dry granulation process readily accommodates both batch and continuous operations. Greater Cost Efficiency In material processing facilities, the key to maximizing profits is adopting more cost-effective processing techniques and technologies.

Applications of Dry Granulation Dry granulation operations are found in a wide range of industries, including the following: The pharmaceutical industry. Within the pharmaceutical industry, the dry granulation process is primarily used to increase material flowability and prevent particle segregation, facilitating faster and more consistent feeding into the tableting process. This results in the formation of slugs.

Slugs are the rough form of tablets, usually quite large in size. Milling or Crushing: The slugs are then milled or crushed until the required granule size is obtained. Depending upon the product requirement, sieves are used to attain granules of the right size. At this stage, further mixing is done with the addition of extragranular excipients. Extragranular excipients do not form the part of the main mixture; instead, they are added after the granulation has taken place.

Extragranular excipients include diluents, disintegrating agents, and others. The materials are then ready as a result of the granulation process in pharmaceutical manufacturing for further compression. Pin it. Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since Sign-up for the free email updates for your daily dose of pharmaceutical tips.

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